产品货号:
Z28769
中文名称:
TNFR2/TNFRSF1B抗体
英文名称:
Anti-TNFR2/TNFRSF1B Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TNFR2/TNFRSF1B Antibody |
指标别名 | CD120b;Etanercept;p75;p75TNFR;p80 TNF alpha receptor;TBP 2;TBPII;TNF R II;TNF R2;TNF R75;TNF Receptor 2;TNF Receptor II;TNF RII;TNFBR;TNFR II;TNFR1B;TNFR2;TNFR80;TNFRSF1B |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,FCM,ELISA |
基因名称 | TNFRSF1B |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human TNF Receptor II/TNFRSF1B recombinant protein (Position:L23-A189). |
实际分子量 | 75KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Tumor necrosis factor receptor 2 (TNFR2) is one of receptors of TNF.TNF has proinflammatory and immunosuppressive properties that may segregate at the level of the 2 TNF receptors (TNFRs),TNFR1 and TNFR2.The genes for TNFR1,a 55-kDa protein,and TNFR2,a 70-kDa protein,have been mapped to human chromosomes 12 (12pter-cen) and 1 (1pter-p32),respectively.TNFR2 was induced on glomerular endothelial cells of nephritic kidneys,and TNFR2 expression on intrinsic cells,but not leukocytes,was essential for glomerulonephritis and glomerular complement deposition.TNFR1 promotes systemic immune responses and renal T cell death,while intrinsic cell TNFR2 plays a critical role in complement-dependent tissue injury.Therefore,therapeutic blockade specifically of TNFR2 may be a promising strategy in the treatment of immune-mediated glomerulonephritis. |
Uniprot ID | P20333 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
基因名全称 | TNF receptor superfamily member 1B |
蛋白名全称 | Tumor necrosis factor receptor superfamily member 1B |
推荐稀释比 | Western blot(WB) 1:500~2000 Flow cytometry (FCM) 1~3μg/1×106 cells ELISA 1:100~1000 |
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